1-Boc-3-piperidinecarboxylic acid
1-(tert-butoxycarbonyl)-3-piperidine-carboxylic acid
CAS: 84358-12-3;71381-75-4
Molecular Formula: C11H19NO4
1-Boc-3-piperidinecarboxylic acid - Names and Identifiers
| Name | 1-(tert-butoxycarbonyl)-3-piperidine-carboxylic acid |
| Synonyms | BOC-NIP BOC-NIP-OH Boc-DL-Nip-OH BOC-DL-NIP-OH BOC-DL-NIPC-OH BOC-DL-PIC(3)-OH BOC-(R,S)-NIP-OH BOC-DL-NIPECOTIC ACID N-Boc-DL-nipecotic acid BOC-3-CARBOXYPIPERIDINE 1-Boc-piperidine-3-carboxylicacid 1-Boc-3-piperidinecarboxylic acid 1-BOC-PIPERIDINE-3-CARBOXYLIC ACID 1-Boc-piperidine-3-carboxylic acid 1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid 1-(tert-butoxycarbonyl)-3-piperidine-carboxylic acid 1,3-Piperidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester N-(tert-Butoxycarbonyl)nipecotic acid~1-(tert-Butoxycarbonyl)piperidine-3-carboxylic acid Boc-DL-Nip-OH~N-(tert-Butoxycarbonyl)nipecotic acid~1-(tert-Butoxycarbonyl)piperidine-3-carboxylic acid |
| CAS | 84358-12-3 71381-75-4 |
1-Boc-3-piperidinecarboxylic acid - Physico-chemical Properties
| Molecular Formula | C11H19NO4 |
| Molar Mass | 229.27 |
| Melting Point | 159-162°C(lit.) |
| Appearance | White to white-like crystals |
| Storage Condition | 2-8℃ |
| MDL | MFCD00673775 |
1-Boc-3-piperidinecarboxylic acid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
1-Boc-3-piperidinecarboxylic acid - Introduction
1-(tert-butoxycarbonyl)-3-piperidine-carboxylic acid, full name 1-(tert-butoxycarbonyl)-3-piperidine-carboxylic acid, is an organic compound.
Properties: 1-(tert-butoxycarbonyl)-3-piperidine-carboxylic acid is a white to light yellow crystalline powder with good solubility and stability. It is a colorless or yellowish solid that is stable at room temperature.
Uses: 1-(tert-butoxycarbonyl)-3-piperidine-carboxylic acid is commonly used as an intermediate in organic synthesis. It plays a role in protecting amino acids in the synthesis of peptides and drugs. In addition, it can also be used as a catalyst in pharmaceutical research and organic synthesis reactions.
Preparation method: The synthesis of 1-(tert-butoxycarbonyl)-3-piperidine-carboxylic acid is usually carried out by reacting N-Boc-DL-diallylamine with dimethyl sulfoxide, followed by crystallization purification to obtain the product.
safety information: 1-(tert-butoxycarbonyl)-3-piperidine-carboxylic acid generally has no obvious effect on human health, but it is still necessary to pay attention to its protective measures. During use, avoid exposure to skin and eyes and wear protective equipment if necessary. Handling of the compound should be carried out in a well-ventilated laboratory and following safe practices. In case of accidental ingestion or contact, seek medical advice immediately.
Properties: 1-(tert-butoxycarbonyl)-3-piperidine-carboxylic acid is a white to light yellow crystalline powder with good solubility and stability. It is a colorless or yellowish solid that is stable at room temperature.
Uses: 1-(tert-butoxycarbonyl)-3-piperidine-carboxylic acid is commonly used as an intermediate in organic synthesis. It plays a role in protecting amino acids in the synthesis of peptides and drugs. In addition, it can also be used as a catalyst in pharmaceutical research and organic synthesis reactions.
Preparation method: The synthesis of 1-(tert-butoxycarbonyl)-3-piperidine-carboxylic acid is usually carried out by reacting N-Boc-DL-diallylamine with dimethyl sulfoxide, followed by crystallization purification to obtain the product.
safety information: 1-(tert-butoxycarbonyl)-3-piperidine-carboxylic acid generally has no obvious effect on human health, but it is still necessary to pay attention to its protective measures. During use, avoid exposure to skin and eyes and wear protective equipment if necessary. Handling of the compound should be carried out in a well-ventilated laboratory and following safe practices. In case of accidental ingestion or contact, seek medical advice immediately.
Last Update：2024-04-09 02:00:48
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